DENARASE ELISA Kit
The DENARASE ELISA Kit has been developed to monitor residual traces of Serratia marcescens endonucleases such as DENARASE and Benzonase* in process samples of biopharmaceutical manufacturing processes. The kit may be used for both process development and quality control purposes.
The DENARASE ELISA Kit uses an antibody sandwich principle in which the endonuclease is captured by two specific monoclonal antibodies. The first antibody is pre-coated on micro test plates and makes the endonucleases adhere to the plate. After washing the plates, a second monoclonal antibody binds specifically with the captured endonuclease. This second antibody can be detected visually and quantified with the help of an enzyme conjugate and substrate solution.
Best in Class Performance
The carefully selected monoclonal antibodies provide an unmatched sensitivity and reproducibility in comparison to similar endonuclease ELISA Kits that work with polyclonal antibodies.
*Benzonase Nuclease is a registered trademark of Merck KGaA